LOSS OF MFN1 BUT NOT MFN2 ENHANCES ADIPOGENESIS.

Loss of Mfn1 but not Mfn2 enhances adipogenesis.

ObjectiveA biallelic missense mutation in mitofusin 2 (MFN2) causes multiple symmetric lipomatosis and partial lipodystrophy, implicating disruption of mitochondrial fusion or interaction with other organelles in adipocyte differentiation, growth and/or survival.In this study, we aimed to document the impact of loss of mitofusin 1 (Mfn1) or 2 (Mfn2

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Pharmacological therapy, slows the heart rate, in patientswith hypertension and chronic heart failure: theory and application in clinical practice

The purpose of the study is to determine the spectrum used drugsslows the heart rate in patients with arterial hypertension and chronic heart failure in clinical practice and compliance of prescribing with clinical guidelines.Materials and methods.Consistently formed a retrospective sample of medical records of patients with arterial Accessories hy

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